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	Toxin Name U2-theraphotoxin-Lsp1a Source Species Lasiodora  sp. Toxin Group Theraphotoxin Description Toxin with unknown activity and molecular target. Isolated from a Lasiodora species from the state of Minas Gerais in Brazil that is closely related to Lasiodora parahybana. Discovered 2007 This toxin last updated on Dec 20, 2009 Taxonomy Current Taxonomy Kingdom Animalia Phylum Arthropoda Class Arachnida Order Araneae Infra-order Mygalomorphae Family Theraphosidae Genus Lasiodora Species sp. Biological Activity Activity not known Molecular Target ED50 IC50 Kd Pharmacophore Comment Molecular target unknown Accessions Source Accession ArachnoServer AS000509 EMBL ABN13623 EMBL EF219061 InterPro IPR012627 NCBI_Taxon 300858 Pfam PF08092 UniProt A3F7X1 Literature References Original Deposition References Castro,I.M., Moura,M.B. and Kalapothakis,E. Direct Submission Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. Protein Information Disulfide Bonds Left Residue Right Residue Evidence 1 16 8 21 15 36 Sequences Peptide Sequences >as:U2-theraphotoxin-Lsp1a|sp:A3F7X1 Toxin with unknown activity from venom of the spider Lasiodora sp. MNTIQVIIFAVVLVLTVTVGQADEDSPEASLLRKLKEAEASLFGQNLEESRNSRQKRCGG VDAPCDKDRPDCCSYAECLRPSGYGWWHGTYYCYRKRER Full BLAST BLAST mature toxin only mRNA Sequences >as:U2-theraphotoxin-Lsp1a|gb:EF219061 cDNA sequence of a toxin from the venom gland of the spider Lasiodora sp. GGCACCAGCTCTTAGATTAAGAAACATGAATACTATACAAGTAATAATATTCGCAGTGGT TTTGGTGTTGACGGTGACCGTAGGACAGGCTGATGAAGATAGTCCTGAAGCTTCGCTCCT TCGAAAACTGAAAGAGGCAGAGGCTTCCCTGTTTGGACAAAACCTAGAAGAAAGCAGAAA TTCTCGGCAGAAGCGATGTGGAGGGGTAGATGCGCCGTGCGATAAAGACCGCCCTGACTG TTGTAGTTACGCCGAATGTCTTAGACCGTCAGGGTACGGATGGTGGCATGGTACATATTA CTGCTATAGAAAAAGGGAACGTTGATTTCCACCTGAGATTGCTGCGATATCCTGTCTGTC TGTTGTCGACTCCGGTGTAAGCAAAAATCTTTGTCGGTATAAGTTTTGCAAAGCAGCTTC ATGAAAAATGGTGTCGGTTTATGTTTCTTTCAGAACAAAAATAAAGTGGAAGAGTATTAC TGTAAAAAAAAAAAAAAAAAAAAA Full BLAST Toxin Synonyms Synonym Type U2-theraphotoxin-Lsp1a Recommended full name U2-TRTX-Lsp1a Recommended abbreviation LTx4 Synonym
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