SpiderP predicts the location (or absence) of propeptides in spider toxins. The program first runs SignalP to search for signal peptides and then looks for propeptides in the remaining sequence using a support vector machine (SVM) algorithm. The program outputs any predicted signal and propeptide sequences as well as the predicted mature peptide region. If a propeptide is present, the residue number that is N-terminal to the propeptide cleavage site will also be reported. Please be aware that it might take some time for the SVM model to load.

All training and testing data are available for download here.

Please input your protein sequence below (in FASTA or multiple FASTA format):